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Research Departments >Functional and Systems Neurobiology department > Microorganization of the normal cerebral cortex and alterations of cortical circuits in brain pathologies> Research Report

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Microorganization of the normal cerebral cortex and alterations of cortical circuits in brain pathologies

The Laboratorio Cajal de Circuitos Corticales (LCCC) principally focuses on the microorganization of the normal cerebral cortex (including hippocampus) in various species (particularly humans) and on the alterations of cortical circuits in epilepsy and Alzheimer disease. These studies are performed through the use of anatomical tracers, high resolution immunocytochemistry and 3D electron microscopy. Another major aim is to develop informatic technologies to examine the brain.

Most relevant methodology

Intracellular injection in fixed tissue; histochemical and inmunocytochemical techniques for optical and electron microscopy and Image processing; 3D reconstruction methods (confocal and FIB/SEM microscopy); tract-tracing anatomical methods; stereology.


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